
Ipriflavone
CAS No. 35212-22-7
Ipriflavone ( Osteofix )
产品货号. M14200 CAS No. 35212-22-7
伊普黄酮(7-异丙氧基异黄酮)用于抑制骨吸收。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
500MG | ¥340 | 有现货 |
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1G | ¥405 | 有现货 |
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生物学信息
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产品名称Ipriflavone
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述伊普黄酮(7-异丙氧基异黄酮)用于抑制骨吸收。
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产品描述Ipriflavone (7-Isopropoxyisoflavon) is used to inhibit bone resorption.(In Vitro):Ipriflavone inhibits the proliferation and DNA synthesis of MDA-231 cells and blocks the ligand-induced phosphorylation of Tyr(845) of the EGFR. Ipriflavone does not promote apoptosis of MDA-231 cells. Ipriflavone also promotes the deposition of calcium and the formation of mineralized nodules by newborn rat calvarial osteoblast-like cells as well as the activity of alkaline phosphatase. (In Vivo):Daily oral administration of ipriflavone at 12 mg/mouse significantly inhibits the development of new osteolytic bone metastases and the progression of established osteolytic lesions, prolonging the life of tumor-bearing mice. Ipriflavone reduces the number of osteoclasts at the bone-cancer interface with no severe adverse effects on the host. 1-month treatment with ipriflavone increases bone density and improves the biomechanical properties of adult rat male bones without altering mineral composition.
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体外实验——
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体内实验——
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同义词Osteofix
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通路Others
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靶点Other Targets
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受体advanced glycation end products
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研究领域Other Indications
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适应症——
化学信息
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CAS Number35212-22-7
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分子量280.32
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分子式C18H16O3
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纯度>98% (HPLC)
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溶解度Ethanol: 2 mg/mL (7.13 mM); DMSO: 56 mg/mL (199.77 mM)
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SMILESO=C1C(C2=CC=CC=C2)=COC3=CC(OC(C)C)=CC=C13
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化学全称7-isopropoxy-3-phenyl-4H-chromen-4-one
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Cheng SL, et al. Calcif Tissue Int, 1994, 55(5), 356-362.
产品手册




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